Thursday, September 4th, 2008

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<p>Dr. Zuo-Feng Zhang speaks at a SARS symposium in Bunche Hall
addressing political, economic and s

Dr. Zuo-Feng Zhang speaks at a SARS symposium in Bunche Hall addressing political, economic and s

SARS sparks spread of research and discussion

A group of professionals discussed the scientific, political, social and economic aspects of severe acute respiratory syndrome at Bunche Hall on Thursday; the impact of the virus hit home for some upon learning that the University of California would not have an Education Abroad Program in Beijing in summer or fall 2003.

SARS has killed 750 people so far and has infected 8,295. Though the number of infections is decreasing, UCLA epidemiologist Roger Detels predicts SARS will follow the path of influenza and “probably have a winter-based cycle;” the infections will probably slow down over the summer but increase as winter approaches.

In the meantime, scientists are working to isolate the virus that causes SARS.

Ren Sun, a member of the department of molecular and medical pharmacology, says an unconfirmed study has found that SARS has a gene sequence that is 99 percent homologous to animal coronavirus. Coronavirus can be found in many different species of animals, including the civet cat, which is eaten in China. Coronavirus has very few, if any, negative effects on its wild animal hosts.

Sun also notes the research done for HIV will be instrumental in developing drugs to fight SARS. SARS, like HIV, is an RNA virus. RNA viruses replicate much faster than DNA viruses and, thus, mutate much more as well. Sun believes the best way to combat SARS is either by inhibiting viral replication or by injecting antibodies into infected individuals.

Viral inhibition, the process of preventing a virus from replicating, is possible because SARS coronavirus contains the enzyme proteinase, which is necessary for replication. Sun explained that by inhibiting the proteinase, the virus will not be able to mature and thus cannot replicate.

The average death rate for SARS is about 9 percent. However, it is as high as 16.67 percent in the Philippines, and as low as 0 percent in the United States, where none of the country’s 66 cases have died.

Zuo-Feng Zhang, a UCLA professor of epidemiology, said the United States might have such a low death rate because of its health care system, but it may also be because the United States had the advantage of seeing SARS cases in other parts of the world before the cases came to the country.

Lynda Bell, former director of the Beijing UC EAP, described the panic SARS caused in Beijing before the program was closed down.

“There’s SARS, and there’s ‘SARS panic system’ – this you can get too, and it’s dangerous,” she said.

Bell said she became paranoid and thought she had the illness after developing a sore throat. She also noted that she washed her hands so much that she said, “at one point, I actually thought I had no skin left on my hands.”

The SARS risk has temporarily closed down the EAP program in Beijing. Students in Beijing were sent home in April, and Bell says the fall program will not take place because the university does not know when students will be able to begin classes or where they will live. The summer program was canceled, as well.

Students at Peking and Beijing Normal universities, where EAP students usually study, are currently quarantined. No new students are allowed access to either campus or the school dorms.