Wednesday, January 7th, 2009

Institute for Cell Mimetic Space Exploration opens

Researchers aim to combine molecular biology with modern technology, improve astronaut health safety

Monday marked the official opening for the new Institute for Cell Mimetic Space Exploration at UCLA.

The joint partnership between UCLA and NASA aims to develop a “lab on a chip,” which would carry out the same complex functions of a full-sized scientific lab on a tiny chip.

Chih-Ming Ho, director for the new institute and associate vice chancellor of research at UCLA, will lead CMISE researchers in combining molecular biology with modern scientific technology. Researchers will apply their knowledge of the biological cell to all facets of space exploration.

“Basically, we want to learn why nature can produce such an efficient system (a single cell) in such a small space,” Ho said.

“Then we can expand this very small space to a very large space.”

The CMISE researchers hope to improve the health monitoring of astronauts and develop radiation-resistant suits which could someday make human travel to Mars possible.

The result, Ho hopes, will potentially make space research safer and more efficient.

“With an automated system, we can conduct scientific tests without risking human lives,” Ho said in a statement.

Although UCLA will be contributing $5 million, the new institute is mainly funded by a five-year, $15 million grant from NASA that can be renewed for an additional five years for a total of $30 million.

“I was excited to learn that we were successful in obtaining the highly competitive NASA center,” said Vijay Dhir, dean of the engineering department at UCLA, after UCLA was awarded the grant last summer.

“It is a recognition of the highest quality research we are doing and of the excellent faculty we have.

The CMISE faculty includes researchers who are leaders in various fields of biological sciences and engineering.

Of the faculty members involved with the institute, two are Nobel laureates and three are academy members, a top science honor.

“These faculty members have a track record of turning scientific dreams into reality,” Ho said.

Along with Ho, the institute will be led by Carlo Montemagno, co-director of CMISE and the Carol and Roy Doumani Professor of Biomedical Engineering at UCLA.

The new institute is an example of the importance of interdisciplinary cooperation and will focus on four primary paths of research: energetics, metabolics, systematics and CMISESat.

Energetics focuses on building nano-sized (one billionth of a meter) power generators for hybrid energy systems.

Metabolics will take biological cells, intracellular components and molecular machines to sense and control single cells.

Systematics will combine both energetics and metabolics, and scale these components into larger devices.

CMISESat, the fourth area of research, will be conducted at Arizona State University to teach students how to build small satellites to be launched into space.

These satellites, weighing about one pound, will be used as models to show that CMISE research will work properly in space.

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